สถาบันวิจัยแสงซินโครตรอน (องค์การมหาชน)

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To find the three-dimensional structure of the protein.

Technique three-dimensional structure relies on the refraction of x-rays of the crystalline compound, large (Macromolecule Crystallography) to form the three-dimensional structure of a biomolecule such nucleic acids and proteins, if we know the structure of a biomolecule such, indeed, is useful in the control function or the mechanism of biomolecule such as to the direction in which to effectively which is useful for the applied Sciences and medical Sciences, the first step is the preparation of single crystals of biomolecules Then single crystal such information refraction of x-rays which is caused by radiation which has a wavelength in the level of x-rays to the incident atoms arranged orderly in the plane of the crystals of the compound molecular model the refraction of x-rays that have called stereotypes refraction of x-rays data processed in order to find a group symmetry and unit cell of the crystals after the processing step, therefore, to find the initial phase, thus leading customization process model structure to find the diagram, the density of electrons to find the perfect structure further.

Technique three-dimensional structure relies on the refraction of x-rays of a crystalline substance

The origin of instagram http://beatrizbiominds.wordpress.com/

Prepare crystals

The origin of instagram http://xray.bmc.uu.se/terese/

Protein crystals

The origin of the figure  Creighton, T. (1993). Proteins: structures and molecular properties. New York: Editorial W. H. Freeman & Co.

Storage refraction of x-rays.

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The origin of instagramhttp://arrowthroughthesun.blogspot.com/2009_08_01_archive.html

Stereotypes refraction of x-rays.

Customize the model structure

The origin of instagram http://www.spring8.or.jp/wkg/BL41XU/solution/lang-en/SOL-0000001166?set_language=en&cl=en  

Diagrams density, electron

The three-dimensional structure of the protein.